Karin Scharffetter-Kochanek Selected Research

Fibrosis (Cirrhosis)

2/2014	TSG-6 released from intradermally injected mesenchymal stem cells accelerates wound healing and reduces tissue fibrosis in murine full-thickness skin wounds.
9/2013	Disclosure of the Culprits: Macrophages-Versatile Regulators of Wound Healing.
3/2013	Tropisetron suppresses collagen synthesis in skin fibroblasts via α7 nicotinic acetylcholine receptor and attenuates fibrosis in a scleroderma mouse model.
2/2009	alpha-melanocyte-stimulating hormone suppresses bleomycin-induced collagen synthesis and reduces tissue fibrosis in a mouse model of scleroderma: melanocortin peptides as a novel treatment strategy for scleroderma?

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Karin Scharffetter-Kochanek Research Topics

Disease

17	Wounds and Injuries (Trauma) 01/2022 - 09/2005
14	Neoplasms (Cancer) 05/2024 - 11/2002
14	Inflammation (Inflammations) 11/2020 - 09/2005
13	Psoriasis (Pustulosis Palmaris et Plantaris) 11/2020 - 08/2006
5	Premature Aging 01/2023 - 07/2002
5	Cockayne Syndrome (Syndrome, Cockayne) 01/2023 - 10/2008
5	Skin Diseases (Skin Disease) 10/2009 - 12/2003
4	Hypersensitivity (Allergy) 01/2023 - 01/2002
4	Fibrosis (Cirrhosis) 02/2014 - 02/2009
3	Mitochondrial Diseases (Mitochondrial Disease) 09/2023 - 01/2017
3	Trichothiodystrophy Syndromes 01/2023 - 11/2021
3	Melanoma (Melanoma, Malignant) 02/2022 - 10/2003
3	Osteoporosis 01/2022 - 04/2011
3	Cicatrix (Scar) 01/2020 - 04/2009
3	Leg Ulcer 01/2019 - 03/2011
3	Vasculitis (Vasculitides) 12/2017 - 02/2007
2	Neoplasm Metastasis (Metastasis) 04/2024 - 11/2002
2	Infections 01/2022 - 03/2020
2	Diabetic Foot 01/2022 - 01/2022
2	Ulcer 01/2022 - 01/2022
2	Dermatitis 01/2018 - 12/2013
2	Edema (Dropsy) 12/2017 - 12/2002
2	Arthus Reaction 12/2017 - 02/2007
2	Localized Scleroderma (Morphea) 02/2016 - 09/2009
2	Systemic Scleroderma (Systemic Sclerosis) 03/2013 - 02/2009
2	Hyperoxia 11/2003 - 10/2002
1	Xeroderma Pigmentosum (Kaposi's Disease) 01/2023
1	Merkel Cell Carcinoma 07/2022
1	Sarcoma (Soft Tissue Sarcoma) 02/2022
1	Hypoxia (Hypoxemia) 01/2022
1	Ischemia 01/2022
1	Varicose Ulcer (Ulcer, Venous) 01/2021
1	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 10/2020
1	Bullous Pemphigoid (Pemphigoid) 10/2020
1	Abscess 08/2020
1	Congenital Microtia 03/2020
1	Leukocyte-Adhesion Deficiency Syndrome 01/2020
1	Choristoma (Ectopic Tissue) 01/2019

Drug/Important Bio-Agent (IBA)

13	Proteins (Proteins, Gene)FDA Link 09/2023 - 10/2005
13	IntegrinsIBA 01/2020 - 01/2002
7	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2022 - 11/2002
6	RNA Polymerase I (Polymerase I, RNA)IBA 01/2023 - 09/2008
3	Ficusin (Psoralen)IBA 01/2020 - 11/2003
3	IronIBA 01/2019 - 03/2011
3	CalciumIBA 01/2018 - 02/2004
3	Antigen-Antibody Complex (Immune Complex)IBA 12/2017 - 02/2007
3	Superoxide DismutaseIBA 01/2016 - 11/2002
3	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 02/2014 - 01/2002
3	CollagenIBA 03/2013 - 02/2009
3	Matrix Metalloproteinases (MMPs)IBA 10/2009 - 07/2002
3	Transforming Growth Factor beta (TGF-beta)IBA 07/2008 - 10/2005
2	RNA Polymerase II (RNA Polymerase B)IBA 01/2023 - 01/2023
2	Messenger RNA (mRNA)IBA 01/2023 - 01/2022
2	CytokinesIBA 08/2020 - 10/2009
2	NADPH Oxidases (NAD(P)H oxidase)IBA 01/2020 - 01/2014
2	Superoxides (Superoxide)IBA 01/2016 - 04/2011
2	Interleukin-17 (Interleukin 17)IBA 04/2015 - 12/2013
2	Imiquimod (Aldara)FDA LinkGeneric 04/2015 - 12/2013
2	Transcription Factors (Transcription Factor)IBA 01/2014 - 10/2009
2	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 09/2013 - 09/2008
2	Bleomycin (Blenoxane)FDA LinkGeneric 03/2013 - 02/2009
2	Clodronic Acid (Clodronate)IBA 09/2012 - 08/2006
2	Liposomes (Liposome)IBA 09/2012 - 08/2006
2	NF-kappa B (NF-kB)IBA 10/2009 - 08/2006
2	CD18 AntigensIBA 07/2008 - 01/2002
2	AntioxidantsIBA 09/2005 - 11/2002
2	Ethanol (Ethyl Alcohol)IBA 11/2003 - 10/2002
2	Hydrogen Peroxide (Hydroperoxide)FDA LinkGeneric 11/2003 - 10/2002
1	A-Form DNA (A-DNA)IBA 01/2023
1	pembrolizumabIBA 07/2022
1	Somatostatin Receptors (Somatostatin Receptor)IBA 07/2022
1	Peptide Receptors (Peptide Receptor)IBA 07/2022
1	Immune Checkpoint InhibitorsIBA 07/2022
1	Radioisotopes (Radionuclides)IBA 07/2022
1	Tyrosine (L-Tyrosine)FDA Link 02/2022
1	CoumarinsIBA 02/2022
1	Phosphotransferases (Kinase)IBA 02/2022
1	ErbB Receptors (EGF Receptor)IBA 02/2022
1	Angiogenesis Inducing Agents (Angiogenesis Factor)IBA 01/2022
1	angiogeninIBA 01/2022
1	transcription factor TFIIE (TFIIE)IBA 11/2021
1	Ribosomal Proteins (Ribosomal Protein)IBA 01/2021
1	Drug CarriersIBA 11/2020
1	Intravenous Immunoglobulins (IVIG)FDA Link 10/2020
1	KalininIBA 10/2020
1	Rituximab (Mabthera)FDA Link 10/2020
1	DNA (Deoxyribonucleic Acid)IBA 01/2020
1	Indicators and Reagents (Reagents)IBA 01/2020
1	Adenosine Triphosphate (ATP)IBA 01/2019
1	Interleukin-1 Receptors (Interleukin 1 Receptor)IBA 01/2019

Therapy/Procedure

26	Therapeutics 05/2024 - 01/2002
3	Phototherapy (Light Therapy) 08/2016 - 09/2008
3	Injections 03/2013 - 02/2004
2	Surgical Amputation (Amputations) 01/2022 - 01/2019
2	Subcutaneous Injections 08/2006 - 02/2004
1	Immunotherapy 07/2022
1	Lasers (Laser) 01/2022
1	Tympanoplasty 03/2020
1	Antibiotic Prophylaxis 03/2020
1	Transplantation 01/2020